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Study Explores the Ability of NOL Technology to Detect Pain in the ICU

A peer-reviewed observational study reveals promising findings regarding the ability of Medasense’s NOL monitor to detect pain response levels in ICU patients.

Pain assessment in the ICU is a huge challenge for clinicians. Many ICU patients are unable to self-report their pain due to their critical condition, and the use of behavioural indicators may be limited particularly in deeply sedated or paralyzed patients.1

The study, just published in the Journal of Pain Research,2 has shown that NOL could detect pain during chest tube removal, compared to a non-nociceptive procedure, correlating with patient’s self-reported pain levels. By helping to detect pain, NOL monitoring shows the capacity to optimize and personalize pain management in the ICU and improve patient outcomes post-surgery.

Read the full press release here.


  1. Devlin J.W, Skrobik Y, Gélinas C, et al. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Critical care medicine. 2018; 46(9), e825–e873.
  2. Gélinas C, Shahiri T S, Richard-Lalonde M, Laporta D, Morin JF, Boitor M, Ferland CE, Bourgault P, Richebé P. Exploration of a Multi-Parameter Technology for Pain Assessment in Postoperative Patients After Cardiac Surgery in the Intensive Care Unit: The Nociception Level Index (NOL)TM. J Pain Res. 2021;14:3723-3731

Video Highlights

The essence of Medasense: Guiding critical care clinicians for optimal pain care

Meeting the challenge of intraoperative pain monitoring

Leading clinicians on the importance of monitoring the patient’s pain response level