Monitoring physiological pain response to enhance recovery

Accurate, continuous and noninvasive nociception monitoring

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How It Works

Stand-alone or connected with Philips IntelliVue patient monitors

User-friendly UI
Available in 12 languages

Commercially available in Europe, Canada, Australia, Israel, Turkey, Latin America

What experts are saying

Video Highlights

How NOL monitoring helps guide TIVA TCI anaesthesia | Dr. Hugo Vereecke

NOL guided analgesia in daily practice with Prof. Philippe Richebé

TV News: Patients in Portugal are getting customized anaesthesia care with NOL


1. Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L.,
Niesters, M., Boon, M., Dahan, A. (2020). Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane
anaesthesia: a randomised controlled trial. British Journal of Anaesthesia [In Press]

2. Meijer, F., Martini, C., Broens, S., Boon, M., Niesters, M., Aarts, L., Olofsen, E., van Velzen, M., Dahan, A. (2019). Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial. Anesthesiology, 130(5), 745-755. doi:10.1097/ALN.0000000000002634

3. Saunders R., Weissbrod R. (2020). Cost benefit of personalizing intraoperative pain management. Presented at ISPOR Virtual Conference, May 2020