Clinical Evidence

NOL monitoring impacting global clinical practice

NOL in Peer-Reviewed Journals

Impact of Nociception Level (NOL) index intraoperative guidance of fentanyl administration on opioid consumption, postoperative pain scores and recovery in patients undergoing gynecological laparoscopic surgery. A randomized controlled trial

Espitalier, F., Idrissi, M., Fortier, A., Bélanger, M.È., Carrara, L., Dakhlallah, S., Rivard, C., Brulotte, V., Zaphiratos, V., Loubert, C., Godin, N., Fortier, L.P., Verdonck, O., Richebé, P.

Clinical characterization of dysautonomia in long COVID-19 patients

Barizien, N., Le Guen, M., Russel, S., Touche, P., Huang, F. & Vallée, A.

Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial

Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.

Assessing the antinociceptive effect of nitrous oxide to tetanic stimulation in anaesthetised patients with new intra-operative nociception monitors

Coulombe, M., Décary, E., Maximos, S., Brulotte, V., Drolet, P., Tanoubi, I., Issa, R., Zaphiratos, V. Verdonck, O., Fortier, L., Godin, N., Idrissi, M., Raft, J., Richebé, P.

A randomized controlled trial comparing nociception level (NOL) index, blood pressure, and heart rate responses to direct laryngoscopy versus videolaryngoscopy for intubation: the NOLint project

Sbeghen, V., Verdonck, O., McDevitt, J., Zaphiratos, V., Brulotte, V., Loubert, C., Tanoubi, I., Drolet, P., Belanger, M. E., Fortier, L. P., Godin, N., Guertin, M. C., Fortier, A., Richebé, P.

Impact of chronic treatment by β1-adrenergic antagonists on Nociceptive-Level (NOL) index variation after a standardized noxious stimulus under general anesthesia: a cohort study

Bergeron, C., Brulotte, V., Pelen, F., Clairoux, A., Bélanger, M., Issa, R., Urbanowicz, R., Tanoubi, I., Drolet, P., Fortier, L., Verdonck, O., Fortier, A., Espitalier, F., Richebé, P.

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.

Exploration of the Nociception Level (NOL™) Index for Pain Assessment during Endotracheal Suctioning in Mechanically Ventilated Patients in the Intensive Care Unit: An Observational and Feasibility Study

T. Shiva Shahiri, Melissa Richard-Lalonde, Philippe Richebé, Céline Gélinas

Does nociception monitor‑guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials

Fleur S. Meijer, Marieke Niesters, Monique van Velzen, Chris H. Martini, Erik Olofsen, Ruth Edry, Daniel I. Sessler, Eveline L. A. van Dorp, Albert Dahan, Martijn Boon

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