Clinical Evidence

NOL monitoring impacting global clinical practice

NOL in Peer-Reviewed Journals

Must Read!

Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial

Fuica R, Krocheck C, Weissbrod R, Greenman D, Freundlich A, Gozal Y.

Must Read!

Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial

Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.

Must read!

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.

Must read!

Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Fleur Meijer, Chris Martini, Suzanne Broens, Martijn Boon, Marieke Niesters, Leon Aarts, Erik Olofsen, Monique van Velzen, Albert Dahan

Nociception and pain assessment during suctioning procedures in mechanically ventilated patients in the intensive care unit: a validation study of the Nociception Level index (NOL™)

Shahiri S, Richebé P, Martel MO, Lavoie P, Gélinas C.

Using an artificial intelligence-based device to investigate pain outcomes in robotic prostatectomy at low pressure pneumoperitoneum: The RALP clinical trial.

Vasdev N, Isherwood L, Feyissa M, et al.

Intraoperative Nociception Monitoring Using the NoL Index: Phase-Specific Assessment of Nociceptive Responses During Spinal Surgery

Khalaila, A., Hasan, M., Berkovich, Y., Sleiman, A., Mangoubi, E., Grach, M., Ibrahim, U., Gutman Tirosh, A., Shpigelman, D., & Shpigelman, A.

A Comparison of the Analgesia Nociception Index and Nociception Level Index Under General Anesthesia With Propofol and Remifentanil

Kempe, H. Kreuzer, M., Schneider, G., Gambús, P., Vide, S.

Nociception level index as a tool of measuring pain objectively in patients with complex regional pain syndrome: a feasibility study

Umar, I., Tenenbaum, A., Tzour, A., Khalaia, A., Grach, M.

Evaluation of the Nociception Level Index (NOL) for Intraoperative Analgesia Monitoring in Pediatrics

Julien-Marsollier, F., Maroun, Y., Tournier, E., Bezia, D., Dahmani, S.

Variations of nociception level (NOL®) measurements during robot-assisted laparoscopic prostatectomy – a monocentric retrospective analysis

Heiden, J., Hoefermann, K., Hoeter, K., Kamuf, J., Kuchen, R., Renz, M., Ruemmler, R., Ziebart, A.

Comparison of Opioid Consumption During Target Controlled Infusion (TCI) Guided By Nociception Level Index (NOL) or Standard Care Undergoing Intracranial Tumor Surgery

Demirel, M. E., Bilgi, H., Akesen, S.

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