Clinical Evidence

NOL monitoring impacting global clinical practice

NOL in Peer-Reviewed Journals

Must Read!

Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial

Fuica R, Krocheck C, Weissbrod R, Greenman D, Freundlich A, Gozal Y.

Must Read!

Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial

Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.

Must read!

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.

Must read!

Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Fleur Meijer, Chris Martini, Suzanne Broens, Martijn Boon, Marieke Niesters, Leon Aarts, Erik Olofsen, Monique van Velzen, Albert Dahan

Effect of nociception level-directed analgesic management on opioid usage in robot-assisted laparoscopic radical prostatectomy: a single-center, single-blinded, randomized controlled trial

Tanaka, N., Kadoya, Y., Suzuka, T., Yamanaka, T., Ida, M., Naito, Y.,Ozu, N., Hori, S., Kawaguchi, M.

The role of surgical tissue injury and intraoperative sympathetic activation in postoperative immunosuppression after breast-conserving surgery versus mastectomy: a prospective observational study

Jacobs L.M., Helder L.S., Albers K.I., Kranendonk J., Keijzer C., Jooste L. AB., Strobbe L. JA., Warlé M. C.

Pain monitoring in intensive care: How does the nociception level index affects treatment and prognosis. A randomized, controlled, double-blind trial.

Çalışkan B, Besir Z, Sen O.

Effects of opioid-based versus opioid-free anaesthesia on blinded nociception level index values during laparoscopic gastric bypass surgery: a secondary analysis of a randomised double-blind trial

Coeckelenbergh S., Oltean T., Secco G,. Dandrifosse, A.C., Clanet, M., Joosten, A.

Neuraxial Anesthesia for Combined Left Nephrectomy and Left Hemicolectomy in a One-Lung Patient

Vailati D., Bonvecchio E., Secco G,. Magistro, C., Basta, B.

A novel non-invasive nociceptive monitoring approach fit for intracerebral surgery: a retrospective analysis

Ruemmler, R., Moravenova, V., Al-Butmeh, S., Fukui-Dunkel, K., Griemert, EV., Ziebart, A.

Effect of nociception level index-guided intra-operative analgesia on early postoperative pain and opioid consumption: a systematic review and meta-analysis

Bornemann-Cimenti, H., Lang-Illievich, K., Kovalevska, K., Brenna, C. T. A., Klivinyi, C.

Nociception level index-guided antinociception versus routine care during remifentanil-propofol anaesthesia for moderate-to-high risk cardiovascular surgery: A randomized trial

Coeckelenbergh, S., Sessler, D. I., Doria, S., Patricio, D., Jaubert, L., Huybrechts, I., Stefanidis, C., Kapessidou, P., Tuna, T., Engelman, E., Barvais, L., Perrin, L.

Influence of Intraoperative Nociception during Hip or Knee Arthroplasty with Supplementary Regional Anaesthesia on Postoperative Pain and Opioid Consumption

Neumann C, Gehlen L, Weinhold L, Straßberger-Nerschbach N, Soehle M, Kornilov E, Thudium M.

Generalizability of nociception level as a measure of intraoperative nociceptive stimulation: A retrospective analysis

Ruetzler, K, Montalvo, M, Rotem, OM, Ekrami, E. Rossler, J., Andres, J. Duran, A., Dahan, A. Gozal, Y., Richebe, P., Farhang, B., Turan, A. Sessler, D.I.

Share with us your experiences, insights and case reports