Clinical Evidence
NOL monitoring impacting global clinical practice
NOL in Peer-Reviewed Journals
Impact of chronic treatment by β1-adrenergic antagonists on Nociceptive-Level (NOL) index variation after a standardized noxious stimulus under general anesthesia: a cohort study
Bergeron, C., Brulotte, V., Pelen, F., Clairoux, A., Bélanger, M., Issa, R., Urbanowicz, R., Tanoubi, I., Drolet, P., Fortier, L., Verdonck, O., Fortier, A., Espitalier, F., Richebé, P.
Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial
Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.
Assessing the antinociceptive effect of nitrous oxide to tetanic stimulation in anaesthetised patients with new intra-operative nociception monitors.
Coulombe, M., Décary, E., Maximos, S., Brulotte, V., Drolet, P., Tanoubi, I., Issa, R., Zaphiratos, V. Verdonck, O., Fortier, L., Godin, N., Idrissi, M., Raft, J., Richebé, P.
Nociception level-guided opioid administration in radical retropubic prostatectomy: a randomised controlled trial
Funcke, S., Pinnschmidt, H.O., Brinkmann, C., Wesseler, S.
Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial
Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.
Exploration of the Nociception Level (NOL™) Index for Pain Assessment during Endotracheal Suctioning in Mechanically Ventilated Patients in the Intensive Care Unit: An Observational and Feasibility Study
T. Shiva Shahiri, Melissa Richard-Lalonde, Philippe Richebé, Céline Gélinas
Impact of intravenous phenylephrine bolus administration on the nociceptive level index (NOL)
Julien Raft, Marie-Andrée Coulombe, Etienne Renaud-Roy, Issam Tanoubi, Olivier Verdonck, Louis-Philippe Fortier, Fabien Espitalier, Philippe Richebe
Does nociception monitor‑guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials
Fleur S. Meijer, Marieke Niesters, Monique van Velzen, Chris H. Martini, Erik Olofsen, Ruth Edry, Daniel I. Sessler, Eveline L. A. van Dorp, Albert Dahan, Martijn Boon
Guiding Opioid Administration by 3 Different Analgesia Nociception Monitoring Indices During General Anesthesia Alters Intraoperative Sufentanil Consumption and Stress Hormone Release
Sandra Funcke, Hans Pinnschmidt, Stefan Wesseler, Charlotte Brinkmann, Burkhard Beyer, Virginija Jazbutyte, Christoph Behem, Constantin Trepte, Rainer Nitzschke
Correlation between incremental remifentanil doses and the Nociception Level (NOL) index response after intraoperative noxious stimuli
Etienne Renaud-Roy, Pierre-André Stöckle, Sarah Maximos, Véronique Brulotte, Lucas Sideris, MD, Pierre Dubé, Pierre Drolet, MD, Issam Tanoubi, Rami Issa, Olivier Verdonck, Louis-Philippe Fortier, Philippe Richebe
Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial
Fleur Meijer, Chris Martini, Suzanne Broens, Martijn Boon, Marieke Niesters, Leon Aarts, Erik Olofsen, Monique van Velzen, Albert Dahan
The nociception level index (NOL) response to intubation and incision in patients undergoing video-assisted thoracoscopic surgery (VATS) with and without thoracic epidural analgesia. A pilot study
Laurent Bollag, Srdjan Jelacic, Carlos Delgado Upegui, Cynthia Wu, Philippe Richebe.
