Clinical Evidence
NOL monitoring impacting global clinical practice
NOL in Peer-Reviewed Journals
Must Read!
Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial
Fuica R, Krocheck C, Weissbrod R, Greenman D, Freundlich A, Gozal Y.
Must Read!
Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial
Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.
Must read!
Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial
Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.
Must read!
Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial
Fleur Meijer, Chris Martini, Suzanne Broens, Martijn Boon, Marieke Niesters, Leon Aarts, Erik Olofsen, Monique van Velzen, Albert Dahan
The opioid-sparing effect of nociception level (NOL) index monitoring for adult patients undergoing surgery: A systematic review and meta-analysis
Bo Jiao B, Chen M, Wang W, Chen C.
Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
Rogobete AF, Bedreag OH, Papurica M, Popovici SE, Bratu LM, Rata A, Barsac CR, Maghiar A, Garofil DN, Negrea M, Petcu LB, Toma D, Dumbuleu CM, Rimawi S, Sandesc D.
Nociception Level Index-Directed Erector Spinae Plane Block in Open Heart Surgery: A Randomized Controlled Clinical Trial
Balan C, Tomescu DR, Valeanu L, Morosanu B, Stanculea I, Coman A, Stoian A, Bubenek-Turconi SI.
Nociception monitors vs. standard practice for titration of opioid administration in general anesthesia: A meta-analysis of randomized controlled trials
Dandan M, Jiahui Ma, Huayong Chen, Dongliang Mu, Hao Kong, Lingzhi Yu
Does NoL monitoring affect opioid consumption during da Vinci prostatectomy?
Niebhagen, F., Golde, C., Koch, T., & Hübler, M
Identification Prediction of acute postoperative pain based on intraoperative nociception level (NOL) index values: the impact of machine learning‑based analysis
Morisson, L., Nadeau-Vallée, M., Espitalier, F. Laferrière-Langlois, P., Idrissi, M., Lahrichi, N., Gélinas, C., Verdonck, O., & Richebé P.
Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial
Fuica R, Krocheck C, Weissbrod R, Greenman D, Freundlich A, Gozal Y.
Identification of the intraoperative antinociceptive effect of intravenous fentanyl using the Nociception Level (NOL) index versus clinical parameters in patients undergoing gynecological laparoscopic surgery: A secondary analysis of the NOLGYN study
Ghiyasinasab, M., Morisson, L., Laferrière-Langlois, P., Geraldo-Demers, M. A., Gélinas, C., NadeauVallée, M., Verdonck, O., Lahrichi, N., & Richebé, P.
Effect of combined intraoperative use of the Nociception Level (NOL) and bispectral (BIS) indexes on desflurane administration
Renaud-Roy, E., Morisson, L., Brulotte, V., Idrissi, M., Godin, N., Fortier, L. P., Verdonck, O., Choinière, M., & Richebé, P.
Nociception level index variations in patients with complex regional pain syndrome: a pilot study
Santella M, Richebé P, Godin N, Brulotte V.
Exploration of a Multi-Parameter Technology for Pain Assessment in Postoperative Patients After Cardiac Surgery in the Intensive Care Unit: The Nociception Level Index (NOL)TM
Gélinas C, Shahiri T S, Richard-Lalonde M, Laporta D, Morin JF, Boitor M, Ferland CE, Bourgault P, Richebé P.
Impact of Nociception Level (NOL) index intraoperative guidance of fentanyl administration on opioid consumption, postoperative pain scores and recovery in patients undergoing gynecological laparoscopic surgery. A randomized controlled trial
Espitalier, F., Idrissi, M., Fortier, A., Bélanger, M.È., Carrara, L., Dakhlallah, S., Rivard, C., Brulotte, V., Zaphiratos, V., Loubert, C., Godin, N., Fortier, L.P., Verdonck, O., Richebé, P.
