Clinical Evidence

NOL monitoring impacting global clinical practice

NOL in Peer-Reviewed Journals

Impact of chronic treatment by β1-adrenergic antagonists on Nociceptive-Level (NOL) index variation after a standardized noxious stimulus under general anesthesia: a cohort study

Bergeron, C., Brulotte, V., Pelen, F., Clairoux, A., Bélanger, M., Issa, R., Urbanowicz, R., Tanoubi, I., Drolet, P., Fortier, L., Verdonck, O., Fortier, A., Espitalier, F., Richebé, P.

Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial

Coeckelenbergh, S., Doria, S., Patricio, D., Perrin, L., Engelman, E., Rodriguez, A., Di Marco, L., Van Obbergh, L., Estebe, J., Barvais, L., Kapessidou, P.

Assessing the antinociceptive effect of nitrous oxide to tetanic stimulation in anaesthetised patients with new intra-operative nociception monitors.

Coulombe, M., Décary, E., Maximos, S., Brulotte, V., Drolet, P., Tanoubi, I., Issa, R., Zaphiratos, V. Verdonck, O., Fortier, L., Godin, N., Idrissi, M., Raft, J., Richebé, P.

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A.

Exploration of the Nociception Level (NOL™) Index for Pain Assessment during Endotracheal Suctioning in Mechanically Ventilated Patients in the Intensive Care Unit: An Observational and Feasibility Study

T. Shiva Shahiri, Melissa Richard-Lalonde, Philippe Richebé, Céline Gélinas

Does nociception monitor‑guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials

Fleur S. Meijer, Marieke Niesters, Monique van Velzen, Chris H. Martini, Erik Olofsen, Ruth Edry, Daniel I. Sessler, Eveline L. A. van Dorp, Albert Dahan, Martijn Boon

Guiding Opioid Administration by 3 Different Analgesia Nociception Monitoring Indices During General Anesthesia Alters Intraoperative Sufentanil Consumption and Stress Hormone Release

Sandra Funcke, Hans Pinnschmidt, Stefan Wesseler, Charlotte Brinkmann, Burkhard Beyer, Virginija Jazbutyte, Christoph Behem, Constantin Trepte, Rainer Nitzschke

Correlation between incremental remifentanil doses and the Nociception Level (NOL) index response after intraoperative noxious stimuli

Etienne Renaud-Roy, Pierre-André Stöckle, Sarah Maximos, Véronique Brulotte, Lucas Sideris, MD, Pierre Dubé, Pierre Drolet, MD, Issam Tanoubi, Rami Issa, Olivier Verdonck, Louis-Philippe Fortier, Philippe Richebe

The nociception level index (NOL) response to intubation and incision in patients undergoing video-assisted thoracoscopic surgery (VATS) with and without thoracic epidural analgesia. A pilot study

Laurent Bollag, Srdjan Jelacic, Carlos Delgado Upegui, Cynthia Wu, Philippe Richebe.

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