Pain Casts A Shadow
On Everyday Life
for Hundreds of Millions of People Worldwide
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AI Technology
Quantifies Pain to Personalize Treatment
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Visualizing Pain
for Confident Pain Management
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Treating Pain is at the Heart of Medicine

Pain is a major clinical, social and economic problem, affecting quality of life for hundreds of millions of people globally and with annual costs exceeding $1T.1,2 Medasense is transforming the way pain is being assessed and treated worldwide.

Through our breakthrough NOL® AI technology and sensor platform, we quantify pain response to optimize care and avoid overmedication. Medasense’s flagship product, PMD-200™, is used in critical care settings, to visualize pain response and personalize treatment. Our pipeline products apply Medasense’s AI capabilities to lead pain prediction, stratification and prevention strategies.

Industry Collaborations and Commercial Partners

Eliminate guesswork and meet clinical challenges in assessing pain and improving analgesia.

Clinical Evidence

Clinical studies have demonstrated the impact that NOL monitoring has on patient safety,3 outcomes and savings,4 including 33% reduction in reported postoperative pain.5

Medasense Academy

Welcome to our online and customized education and training program for clinicians and commercial partners.

Latest News

New study shows that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology.


Press release: Monitoring pain response levels during surgery with NOL technology can help reduce postoperative pain as well as healthcare costs.


NOL pain response monitoring has been approved for marketing in Brazil.


Global Distribution Network

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Video Highlights

Medasense - Our Vision: Transforming the way pain is being assessed and treated worldwide

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Meeting the challenge of intraoperative pain monitoring

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Leading clinicians on the importance of monitoring the patient’s pain response level

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1. Darrell J. Gaskin, Patrick Richard. The Economic Costs of Pain in the United States. The Journal of Pain, 2012; 13 (8): 715 DOI: 10.1016/j.jpain.2012.03.009
2. EuroStat. Eurostat News release. Eurostat. [Online] 3 30, 2017. 52/2017.
3. Meijer, F., Martini, C., Broens, S., Boon, M., Niesters, M., Aarts, L., Olofsen, E., van Velzen, M., Dahan, A. (2019). Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial. Anesthesiology, 130(5), 745-755. doi:10.1097/ALN.0000000000002634
4. Saunders R., Weissbrod R. (2020). Cost benefit of personalizing intraoperative pain management. Presented at ISPOR Virtual Conference, May 2020
5. Meijer, F., Honing, M., Roor, T., Toet, S., Calis, P., Olofsen, E., Martini, C., van Velzen, M., Aarts, L., Niesters, M., Boon, M., Dahan, A. (2020). Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial. British Journal of Anaesthesia, 125(6), 1070-1078.